Product Overview
Povidone iodine is a complex of povidone K30 with iodine, which has a strong killing effect on bacteria, viruses, fungi, molds and spores. Stable, non-irritating, completely water soluble.
Product Attributes
Pharmacopoeia Name: Povidone Iodine, Povidone-Iodine (USP), Povidone-Iodinated (EP)
Chemical Name: Complex of polyvinylpyrrolidone with iodine
INCI/CTFA: PVP-Iodine
CAS No.: 25655-41-8
Mechanism of action : PVP is a hydrophilic polymer that has no antibacterial effect. However, due to its affinity for cell membranes, it can directly lead iodine to the cell surface of bacteria, which offers great significance for improving the antibacterial activity of iodine. The target of iodine is the bacterial cytoplasm and cytoplasmic membrane, which kills bacteria immediately in a matter of seconds. When the molecules necessary for the survival of organisms such as sulfhydryl compounds, peptides, proteins, lipids and cytosine are contacted with PVP-I, they are immediately oxidized or iodinated by iodine to lose their activity and achieve a long-term bactericidal action.
Quality Standard
|
Pharmacopoeia standard
|
Appearance
|
Effective iodine /%
|
Residue on ignition/%
|
Loss on drying /%
|
Iodine ion /%
|
Arsenic salt/ppm
|
Heavy metal / ppm
|
Nitrogen content /%
|
PH value (10% aqueous solution)
|
|
CP2010
|
Reddish brown to yellow brown amorphous powder
|
9.0-12.0
|
≤0.1
|
≤8.0
|
≤6.6
|
≤1.5
|
≤20
|
9.5-11.5
|
/
|
|
USP32
|
≤0.025
|
≤8.0
|
≤6.6
|
/
|
≤20
|
9.5-11.5
|
/
|
|
EP7.0
|
≤0.1
|
≤8.0
|
≤6.0
|
/
|
/
|
/
|
1.5-5.0
|
Effective iodine 20% (enterprise standard)
|
Appearance
|
Effective iodine /%
|
Residue on ignition/%
|
Loss on drying /%
|
Iodine ion /%
|
Arsenic salt/ppm
|
Heavy metal / ppm
|
Nitrogen content /%
|
|
Reddish brown to yellow brown amorphous powder
|
18.5-21.0
|
≤0.1
|
≤8.0
|
≤13.5
|
≤1.5
|
≤20
|
8.0-11.0
|
Packing and storage
25KG/cardboard drum, , sealed, kept in a cool dry and dark place.
